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Vol. 72, No. 1
ISSN: 1488-2159
February 2006


Blistering Mucocutaneous Diseases of the Oral Mucosa — A Review: Part 2. Pemphigus Vulgaris


• Mark R. Darling, MSc (Dent), MSc (Med), MChD (Oral Path) •
• Tom Daley, DDS, MSc, FRCD(C) •

A b s t r a c t

Oral mucous membranes may be affected by a variety of blistering mucocutaneous diseases. In this paper, we review the clinical manifestations, typical microscopic and
immunofluorescence features, pathogenesis, biological behaviour and treatment of pemphigus vulgaris. Although pemphigus vulgaris is not a common disease of the oral
cavity, its potential to cause severe or life-threatening disease is such that the general dentist must have an understanding of its pathophysiology, clinical presentation and


MeSH Key Words: mouth diseases; pemphigus/drug therapy; pemphigus/etiology
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