CDA Essentials 2017 • Volume 4 • Issue 6

28 | 2017 | Issue 8 S upporting Y our P ractice peripheral edema, blurred vision, weight gain and inability to concentrate. 20 Benzodiazepines Benzodiazepines are commonly prescribed for the treatment of acute muscle spasm and sleep disorders. Since they have the potential for tolerance and dependence, they should only be considered in consultation with the patient’s physician. Efficacy Some studies show that diazepam significantly reduces chronic jaw pain, 16 and that a 1-month regimen reduces pain associated with TMD. 67 However, other studies only found sleep improvement. 68 Adverse effects and drug interactions Adverse effects include tolerance and dependence. 66 The use of benzodiazepines for TMD has been discouraged because of reactions such as drowsiness, confusion, amnesia and impaired coordination. Abrupt discontinuation may result in withdrawal symptoms. Contraindications to their use include allergy, myasthenia gravis and acute narrow- angle glaucoma. 4 Many benzodiazepines interact with other drugs, as these medications are CYP 4503A4 substrates. Concomitant foods (e.g., grapefruit juice) and drugs (e.g., azole antifungals, erythromycin and calcium channel-blockers that inhibit the 3A4 isoform) can significantly reduce the metabolism of benzodiazepines and lead to elevated levels in the blood and enhanced CNS depression. 4,20 a References Complete listofreferencesavailableat: FIGARO CROWNS THE STRONGEST. THE PRETTIEST. THE BESTVALUE. ALLWHITE PEDIATRICCROWNS Free shipping on orders over $250. • MADE IN THE USA $ 15. 25 USD PER CROWN Don’t waste time and money with Zirconia and Strip Crowns. If you know how to place a stainless steel crown, you already know how to deliver the natural looking Figaro Crowns. Listen to parents’ & patients’ wishes for a more natural looking pediatric crown solution. FIGARO CROWN #62 FIGARO CROWN #54 FIGARO CROWN #54 METAL FREE + BPA FREE NO GST/HST FIGARO CROWNS only takes 1/2 the time